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Phosphoproteomic characterization of viral infection

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Phosphoproteomic Characterization of Viral Infection

INSTITUTE OF BIOTECHNOLOGY AND DEPARTMENT OF BIOSCIENCES

FACULTY OF BIOLOGICAL AND ENVIRONMENTAL SCIENCES DOCTORAL PROGRAMME IN INTEGRATIVE LIFE SCIENCE UNIVERSITY OF HELSINKI

SANDRA SÖDERHOLM

dissertationesscholaedoctoralisadsanitateminvestigandam

universitatishelsinkiensis

28/2016

28/2016

Helsinki 2016 ISSN 2342-3161 ISBN 978-951-51-2087-8

SANDRA SÖDERHOLM Phosphoproteomic Characterization of Viral Infection

Recent Publications in this Series

9/2016 Xiang Zhao

HMGB1 (Amphoterin) and AMIGO1 in Brain Development 10/2016 Tarja Pääkkönen (Jokinen)

Benign Familial Juvenile Epilepsy in Lagotto Romagnolo Dogs 11/2016 Nora Hiivala

Patient Safety Incidents, Their Contributing and Mitigating Factors in Dentistry 12/2016 Juho Heinonen

Intravenous Lipid Emulsion for Treatment of Local Anaesthetic and Tricyclic Antidepressant Toxicity

13/2016 Riikka Jokinen

Genetic Studies of Tissue-Specific Mitochondrial DNA Segregation in Mammals 14/2016 Sanna Mäkelä

Activation of Innate Immune Responses by Toll-like Receptors and Influenza Viruses 15/2016 Mari Hirvinen

Immunological Boosting and Personalization of Oncolytic Virotherapies for Cancer Treatment 16/2016 Sofia Montalvão

Screening of Marine Natural Products and Their Synthetic Derivatives for Antimicrobial and Antiproliferative Properties

17/2016 Mpindi John Patrick

Bioinformatic Tools for Analysis, Mining and Modelling Large-Scale Gene Expression and Drug Testing Datasets

18/2016 Hilla Sumanen

Work Disability among Young Employees Changes over Time and Socioeconomic Differences 19/2016 Oyediran Olulana Akinrinade

Bioinformatic and Genomic Approaches to Study Cardiovascular Diseases 20/2016 Prasanna Sakha

Development of Microfluidic Applications to Study the Role of Kainate Receptors in Synaptogenesis

21/2016 Neha Shrestha

Mesoporous Silicon Systems for Oral Protein/Peptide-Based Diabetes Mellitus Therapy 22/2016 Tanja Holopainen

Targeting Endothelial Tyrosine Kinase Pathways in Tumor Growth and Metastasis 23/2016 Jussi Leppilahti

Variability of Gingival Crevicular Fluid Matrix Metalloproteinase -8 Levels in Respect to Point- of-Care Diagnostics in Periodontal Diseases

24/2016 Niina Markkula

Prevalence, Predictors and Prognosis of Depressive Disorders in the General Population 25/2016 Katri Kallio

The Roles of Template RNA and Replication Proteins in the Formation of Semliki Forest Virus Replication Spherules

26/2015 Hanna Paatela

Role of Dehydroepiandrosterone in High-Density Lipoprotein-Mediated Vasodilation and in Adipose Tissue Steroid Biosynthesis

27/2016 Johanna Mäkelä

Neuroprotective Effects of PGC-1α Activators in Dopaminergic Neurons

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Institute of Biotechnology and Department of Biosciences Faculty of Biological and Environmental Sciences

University of Helsinki Helsinki, Finland

Finnish Institute of Occupational Health Unit of Systems Toxicology

Helsinki, Finland

Doctoral School in Health Sciences Doctoral Programme in Integrative Life Science

PHOSPHOPROTEOMIC CHARACTERIZATION OF VIRAL INFECTION

Sandra Söderholm

ACADEMIC DISSERTATION

To be presented for public examination with the permission of the Faculty of Biological and Environmental Sciences of the University of Helsinki in lecture hall 5,

Latokartanonkaari 7 (Building B), on May the 20th at 12 noon.

Helsinki 2016

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Phosphoproteomic Characterization of Viral Infection

INSTITUTE OF BIOTECHNOLOGY AND DEPARTMENT OF BIOSCIENCES

FACULTY OF BIOLOGICAL AND ENVIRONMENTAL SCIENCES DOCTORAL PROGRAMME IN INTEGRATIVE LIFE SCIENCE UNIVERSITY OF HELSINKI

SANDRA SÖDERHOLM

dissertationesscholaedoctoralisadsanitateminvestigandam

universitatishelsinkiensis

28/2016

28/2016

Helsinki 2016 ISSN 2342-3161 ISBN 978-951-51-2087-8

SANDRA SÖDERHOLM Phosphoproteomic Characterization of Viral Infection

Recent Publications in this Series

9/2016 Xiang Zhao

HMGB1 (Amphoterin) and AMIGO1 in Brain Development 10/2016 Tarja Pääkkönen (Jokinen)

Benign Familial Juvenile Epilepsy in Lagotto Romagnolo Dogs 11/2016 Nora Hiivala

Patient Safety Incidents, Their Contributing and Mitigating Factors in Dentistry 12/2016 Juho Heinonen

Intravenous Lipid Emulsion for Treatment of Local Anaesthetic and Tricyclic Antidepressant Toxicity

13/2016 Riikka Jokinen

Genetic Studies of Tissue-Specific Mitochondrial DNA Segregation in Mammals 14/2016 Sanna Mäkelä

Activation of Innate Immune Responses by Toll-like Receptors and Influenza Viruses 15/2016 Mari Hirvinen

Immunological Boosting and Personalization of Oncolytic Virotherapies for Cancer Treatment 16/2016 Sofia Montalvão

Screening of Marine Natural Products and Their Synthetic Derivatives for Antimicrobial and Antiproliferative Properties

17/2016 Mpindi John Patrick

Bioinformatic Tools for Analysis, Mining and Modelling Large-Scale Gene Expression and Drug Testing Datasets

18/2016 Hilla Sumanen

Work Disability among Young Employees Changes over Time and Socioeconomic Differences 19/2016 Oyediran Olulana Akinrinade

Bioinformatic and Genomic Approaches to Study Cardiovascular Diseases 20/2016 Prasanna Sakha

Development of Microfluidic Applications to Study the Role of Kainate Receptors in Synaptogenesis

21/2016 Neha Shrestha

Mesoporous Silicon Systems for Oral Protein/Peptide-Based Diabetes Mellitus Therapy 22/2016 Tanja Holopainen

Targeting Endothelial Tyrosine Kinase Pathways in Tumor Growth and Metastasis 23/2016 Jussi Leppilahti

Variability of Gingival Crevicular Fluid Matrix Metalloproteinase -8 Levels in Respect to Point- of-Care Diagnostics in Periodontal Diseases

24/2016 Niina Markkula

Prevalence, Predictors and Prognosis of Depressive Disorders in the General Population 25/2016 Katri Kallio

The Roles of Template RNA and Replication Proteins in the Formation of Semliki Forest Virus Replication Spherules

26/2015 Hanna Paatela

Role of Dehydroepiandrosterone in High-Density Lipoprotein-Mediated Vasodilation and in Adipose Tissue Steroid Biosynthesis

27/2016 Johanna Mäkelä

Neuroprotective Effects of PGC-1α Activators in Dopaminergic Neurons

Viittaukset

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