This study was carried out at the Institute of Dentistry, University of Helsinki, Finland and it was supported by grants from the Miina Sillanpää Foundation and the Finnish Dental Society Apollonia. I am grateful to late Professor Jukka Ainamo, the former Dean of the Institute of Dentistry and Professor Jarkko Hietanen, the present Dean of the Institute of Dentistry for the facilities placed at my disposal. I also would like to thank Jukka Ainamo for his encouragement and support in the early phases of this work.
I am deeply grateful to my supervisor, Professor Anja Ainamo for giving me an opportunity to be a part of Helsinki Aging Study. She has gently and patiently introduced the world of research to me and guided me through this process. I appreciate her expertise and friendship tremendously.
I am also deeply indebted to Professor Timo Närhi, my other supervisor. His role changed from co-worker to supervisor through out the years, and his constant support and the occasional gentle push forward have made the completion of this thesis possible. He has been a tireless advisor, always finding time to answer my questions with his expert knowledge. It has been a privilege to work under his guidance and have him as a friend.
I wish to thank my co-authors Miira Vehkalahti, Shilpi Ajwani, Juhani Wolf and Reijo Tilvis, for their valuable input into the study. Miira VehkaIahti deserves also my gratitude for sharing her scientific insight, inspiration and support. I also would like to thank my colleagues and coworkers in the HAS team Juha Nevalainen, Kari Soikkonen, Klaus Schmidt-Kaunisaho, Maarit Saario, Niina Kurki and Kaija Hiltunen for their hard work collecting the data. Kaija Hiltunen is especially thanked for all the inspiring conversations and encouragement in the final phases of my thesis.
I sincerely thank Professor Liisa Suominen, University of Eastern Finland, and
Professor James Newton, University of Aberdeen, the official reviewers of this
thesis, for their careful review. Their expert knowledge, constructive criticism and suggestions for improvements have helped me to improve and clarify the manuscript.
Many thanks to all my colleagues and personnel at the Institute of Dentistry for their help and especially Terhi Karaharju-Suvanto, Eva Siren, Ritva Lindblad and Heli Hirvikangas for their friendship and support. Katja Narva is thanked for her help and encouragement and friendship. My warmest thanks go to my dear friends Annamari Nihtilä and Ulla Piltz for always being there for me.
I also acknowledge Donald Smart for revising the language of this thesis. The personnel of the library at the Institute of Dentistry are thanked for providing me with all the references I needed.
I want to thank my parents and my dear sister Riikka and her family for always unconditionally loving, encouraging and supporting me.
Finally, I express my warmest gratitude to my husband Mikko and our children Aku and Jonatan, for their love and understanding and all the joy in life they give me.
Helsinki, April 2013
Päivi Siukosaari
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