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Heart Disease on a Dish

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List of Errata

1- Page vii line 6 , ´´, and´´ to be deletd.

2- Page xiii 2.19 font index 3- Page xiv 2.31 to be added

4- Page 41, Fig 8 (c) edited (appeares cropped in the bottom in the thesis)

5- Page 41 line 4 – spelling to be changed, regulation 6- Page 44, line 6- spelling to be changed, isolation

7- Page 53 last word, 8-12 days to be deleted, 12-14 days to be edited 8- Page 57, 6th line from below, MEAs with 1 well, 6 wells to 96 wells 9- Page 58, line 1, ´´a´´ needs to be deleted before complementary

10-Page 58, paragraph 2 , line 5, ´´along with cardiac-fibroblasts´´ needs to be deleted 11- Page 61, Table 2, point 3, last line needs to be deleted, it is a repeated in the first line 12- Page 62, line 2, have used LQTS models (instead of LQT2 models)

13-Page 63, second last paragraph, title font, title numbering 2.30 Drug developement and cardiotoxicity screening 14- Page 64, title numbering 2.31

15- Page 66, blank, needs to be deleted

16-Page 67, numbering of title, 3 AIMS OF THE STUDY 17-Page 68, numbering of the title, 4 METHODS

18- Page 68, paragraph 2, line 3 and 4 LMNA and line 7, KCNH2 should be in ITALICS 19-Page 71, edited figure

20-Page 78, numbering of the title, 5 RESULTS

21- Page 79, 2nd paragraph, line 4, delete word ´´were´´

22- Page 94, last paragraph, needs font correction

23-Page 96, second last paragraph, needs font correction

0% KSR 0% KSR

Ascorbic acid 0% KSR

END 2 Method (iPSCs grown on MEFs, seeded on End2 cells for differentiation) Small Molecule Method (iPSCs grown without feeder cells, seeded on Geltrex coated plates for differentiation)

Day 13 Day 6

0% KSR Ascorbic acid

0% KSR Ascorbic acid

0% KSR Ascorbic acid

10% KSR

10% KSR

10% KSR RPMI+B27 -Insulin

CHIR99021

RPMI+B27 -Insulin

RPMI+B27 -Insulin IWP4

RPMI+B27 -Insulin

RPMI+B27 -Insulin

RPMI+B27 +Insulin

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